Profhilo® H+L (1 x 2ml)

Profhilo® H+L: Advanced Hyaluronic Acid Treatment for Skin Remodeling

Product Description
Profhilo® H+L is a stabilized hyaluronic acid (HA) formulation designed specifically for skin remodelling and addressing skin laxity, rather than simply filling lines and wrinkles. It is ideal for use in areas affected by skin laxity, such as the malar and submalar regions of the face. Profhilo® H+L nourishes dermal cells, restores skin firmness, and significantly improves tissue quality, even in challenging areas. This treatment is also an excellent complement to other aesthetic procedures and dermal filler treatments, helping to tighten and rejuvenate the skin.

Presentation/Quality
The product is provided in a single 2.0ml prefilled syringe, along with two 29G 1/2” needles, two traceability labels, and a package insert.

Main Benefits
Profhilo® H+L is an innovative beauty enhancer developed by IBSA Farmaceutici Italia. As the first FDA-approved filler of its kind, it features a stabilized hyaluronic acid base without any cross-linking agents. Utilizing NAHYCO™ Hybrid Technology, this product combines low- and high-molecular-weight hyaluronic acid for enhanced longevity and sustainability. Profhilo® H+L delivers a lifting and volumizing effect, hydrates the skin, and stimulates collagen and elastin production. The result is a significant improvement in skin integrity and laxity, leaving the skin rejuvenated and refreshed.

Ingredients
Profhilo® H+L contains 64mg/ml of hyaluronic acid, composed of half high-molecular-weight and half low-molecular-weight hyaluronic acid.

Ingredients Information
The hyaluronic acid used in Profhilo® H+L is derived from the biofermentation of Streptococcus zooepidemicus and is ultrapure, sterile, and high-grade. Unlike common cross-linked structures, this HA is created using NAHYCO Hybrid Technology, which employs thermal energy to form a highly concentrated HA. The formulation includes 32mg of low-molecular-weight HA (80–100 kDa) and 32mg of high-molecular-weight HA (1100–1400 kDa), encapsulated in a sterile, thick gel with low extrusion force for easier administration.

This innovative design provides Profhilo H+L with high resistance to enzymatic breakdown and inflammatory responses. It enhances elastin expression in fibroblasts, strengthening the cellular matrix to combat skin depressions and volume loss. The slow release of HA stimulates all four types of collagen and elastin, replenishing hydration and restoring skin elasticity and tone. Profhilo H+L’s biocompatibility ensures that it naturally revitalizes the skin, giving it a fuller, plumper, and more youthful appearance.

Use Instructions

How to Use Profhilo H+L
Before treatment, thoroughly disinfect and clean the target areas to prevent infection. Only licensed practitioners should perform this procedure. IBSA recommends using the Bio Aesthetic Points (BAP) technique, which involves injecting 0.2ml of the product into the deep dermis at five specific points on the face: the malar area, submalar area, root of the nasolabial fold, pre-tragal area, and marionette lines. This technique maximizes gel diffusion while avoiding major blood vessels. The product’s low viscosity allows for smooth application with a 29G needle. After injection, gently massage the treated areas to ensure even distribution of the gel.

When to Use Profhilo H+L
This dermal filler is ideal for aging skin experiencing reduced laxity. It is used to restore skin turgor and firmness, effectively treating sagging cheeks and jowls.

Target Areas
Profhilo H+L is most effective in the malar and submalar areas of the face, particularly for sagging cheeks and jowls. It should be applied using the five-point BAP technique as recommended.

Duration of Effects
The effects of Profhilo H+L, including improved skin elasticity and firmness, can last up to six months. For prolonged results, consult with your licensed practitioner to schedule maintenance treatments tailored to your skin’s condition.

Treatment Duration
An initial treatment with Profhilo H+L requires two sessions spaced one month apart. The procedure has no recovery time, and results are visible immediately. Follow-up maintenance sessions should be planned based on individual response to the treatment. Patients are advised not to apply makeup for 12 hours post-treatment and to avoid sun exposure or high temperatures for a week.

By following these guidelines, Profhilo H+L can provide significant, long-lasting improvements in skin quality and firmness, helping patients achieve a rejuvenated, youthful appearance.